organic food

The Environmental Working Group (EWG) released its newest Shopper’s Guide to Pesticides on Monday, which is Earth Day. And apples top its annual “Dirty Dozen” list of fruits and vegetables with the highest pesticide residues for the third year in a row. 
More on Shine: Another Reason to Eat Organic

Other changes from the 2012 findings: cherry tomatoes and hot peppers are newcomers this year. Blueberries and lettuce, meanwhile, dropped off the Dirty Dozen list. The environmental watchdog group uses data compiled by the USDA, based on pre-washed samples of 48 types of conventionally-grown fruits and vegetables, to produce its findings.
More on Yahoo!: Colle Farmers Market Reacts to Organic Farming Boom in Russia

“I think most Americans would be very surprised about how prevalent pesticide residue is,” EWG senior analyst Sonya Lunder told Yahoo! Shine, noting that pesticides were still seen on 67 percent of the samples, which were all either washed or peeled before being tested.

Among the top three worst offenders—apples, strawberries and grapes—nearly every sample had pesticides on it, Lunder said, with one grape alone showing traces of 15 pesticides.

The National Institute of Environmental Health Services acknowledges that scientists do not have a full understanding of the health risks associated with exposure to pesticide residues through food, soil, water, or air. Still, notes EWG, various U.S. and international government agencies have linked pesticides to a slew of health risks, including cancer, hormone disruption, brain and nervous system toxicity and irritation to the skin, eyes and lungs.

Dirty Dozen 2013:

Apples
Strawberries
Grapes
Celery
Peaches
Spinach
Sweet bell peppers
Nectarines (imported)
Cucumbers
Potatoes
Cherry tomatoes
Hot peppers

Additionally, the EWG added a “plus” category for the second year, noting two items—domestically-grown summer squash, plus kale and collards—that, though they didn’t meet Dirty Dozen standards, were commonly contaminated with exceptionally toxic pesticides. These organophosphates, dangerous to the nervous system, were phased out of agricultural use in the 1970s and ’80s, but still linger on many farm fields.

Still, there’s also good news, as the guide includes the “Clean Fifteen”—fruits and veggies with the lowest levels of pesticides, offering hopeful solutions for anyone not in the position to find or pay for more expensive organics. Many of these safest options have naturally protective coatings, such as corn, which tops that list once again this year, and papaya, which is a newcomer. Watermelon, sadly, dropped off the clean list from 2012.

“The health benefits of a diet rich in fruits and vegetables outweigh the risks of pesticide exposure,” notes the EWG report, stressing that “eating conventionally-grown produce is far better than not eating fruits and vegetables at all.”

Clean Fifteen 2013:

Corn
Onions
Pineapple
Avocados
Cabbage
Sweet peas (frozen, since they’re more readily available)
Papayas
Mangoes
Asparagus
Eggplant
Kiwi
Grapefruit
Cantaloupe
Sweet potatoes
Mushrooms

The consumer list, Lunder said, “shows the real difference you can make in your purchasing habits, even if you’re only buying conventional.”
Related:
The Bottom Line: Is Organic Food Really Any Healthier?
6 Tips for Finding Cheap Organic Food
Is Organic Food Healthier? New Study Fuels the Debate


Raw foodism (or rawism) is the practice of consuming uncooked, unprocessed, and often organic foods as a large percentage of the diet.
Depending on the type of lifestyle and results desired, raw food diets may include a selection of raw fruits, vegetables, nuts, seeds (including sprouted whole grains such as gaba rice), eggs, fish (such as sashimi), meat (such as carpaccio), and non-pasteurized/non-homogenized dairy products (such as raw milk, raw milk cheese, and raw milk yogurt).[1]

Early proponents include St. Louis Estes, Edmund Bordeaux Szekely, Johnny Lovewisdom, Ann Wigmore and Viktoras Kulvinskas (co-founders of the Hippocrates Health Institute), Arnold Ehret (author and advocate of fasting), Aris Latham (of Sunfired Foods, Inc., known as the godfather of raw food), Arshavir Ter Hovannessian[41] and Norman W. Walker (who advocated the consumption of vegetable juices).
Notable contemporary proponents include several chefs, published authors and lecturers, such as Dr. Douglas Graham, Rene Oswald, Matthew Kenney, Tonya Zavasta, Alissa Cohen, Aris Latham, Aajonus Vonderplanitz, and Elijah Joy, as well as representatives from rawfood producing companies, such as Natural Balance Food‘s founder, Jamie Combs.
Celebrity proponents include Demi Moore, Woody Harrelson, Jason Mraz, Ben Vereen and Carol Alt. Woody Harrelson has published books on raw food, starred in a raw food film, created a raw food website[42] and also opened O2, a raw food restaurant and bar. Model and actress Carol Alt includes raw animal products in her diet; she has written several books on her version of the raw diet and lifestyle.
Interest in the “Raw Foods Movement” continues to grow today[43] and is especially prevalent in Australia and the western United States,[44] like California.[45] In Europe, it has remained a novelty, although a few restaurants have opened in the UK,[10] Germany,[46] and other large cities.[47] Numerous all-raw cookbooks have been published.[48]
Supercharge Me! 30 Days Raw is a feature-length documentary film about the raw foods diet, made by Jenna Norwood, a former public relations consultant turned independent filmmaker, health educator and raw food chef.[49] In the film, inspired by Morgan Spurlock‘s Super Size Me, Jenna ate only raw foods for thirty days, to document the effect it would have on her health.

Richard Wrangham, a primate researcher and professor of anthropology, has suggested that eating cooked food is more “natural” for the human digestive system, because he thinks that the human digestive system may have evolved to deal with cooked foods.[130][131] Wrangham thinks that cooking explains the increase in hominid brain sizes, smaller digestive tract, smaller teeth and jaws and decrease in sexual dimorphism that occurred roughly 1.8 million years ago.[130][131] Most other anthropologists oppose Wrangham,[132] stating that archeological evidence suggests that cooking fires began in earnest only c.250,000 years ago, when ancient hearths, earth ovens, burnt animal bones, and flint appear across Europe and the Middle East. Two million years ago, the only sign of fire is burnt earth with human remains, which most other anthropologists consider to be mere coincidence rather than evidence of intentional fire.[133] The mainstream view among anthropologists is that the increases in human brain-size occurred well before the advent of cooking, due to a shift away from the consumption of nuts and berries to the consumption of meat.[134][135]

Managing Vata Dosha

One of the most important lifestyle tools for maintaining health and for supporting healing in the vata individual is the adoption of regular healthy routines that are in harmony with the rhythms of nature. Stability is greatly improved through eating and sleeping at the same times every day.

It is best to arise within a half hour of the sun rising. The morning routine should include time for self abhyanga (oil massage), meditation and yoga asana practice in addition to proper daily hygiene. Meals should be taken regularly throughout the day; as many as five small meals per day taken every three hours would be appropriate. These meals should be taken at the same time each day. This increases both the heavy and stable qualities. The foods should be somewhat oily (moist), cooked when possible (warm) and moderately spiced (warm). Bed time should occur at about 9:00 or 10:00 , though this depends somewhat on the rhythm of the sunset and varies season to season and by latitude. Waking and sleeping times should be consistent from day to day (stability).
– See more at: http://www.ayurvedacollege.com/articles/drhalpern/Vata_Doshas#sthash.PfQn85v2.dpuf

dosha

"Ayurveda humors" by Krishnavedala - Own work. Licensed under CC0 via Wikimedia Commons.
Ayurveda humors” by KrishnavedalaOwn work. Licensed under CC0 via Wikimedia Commons.

A dosha (doṣa), according to Ayurveda, is one of three bodily humors that make up one’s constitution. These teachings are also known as the Tridosha theory.

The central concept of Ayurvedic medicine is the theory that health exists when there is a balance between three fundamental bodily humours or doshas called Vata, Pitta and Kapha.

  • Vāta or Vata (wind) is the impulse principle necessary to mobilize the function of the nervous system. It affects the windy humour, flatulence, gout, rheumatism, etc.[1][2]
  • Pitta is the bilious humour, or that secreted between the stomach and bowels and flowing through the liver and permeating spleen, heart, eyes, and skin; its chief quality is heat.[3] It is the energy principle which uses bile to direct digestion and hence metabolism.
  • Kapha is the body fluid principle which relates to mucus, lubrication, and the carrier of nutrients.

All Ayurvedic physicians believe that these ancient ideas, based in the knowledge discovered by the Rishis and Munis, exist in harmony with physical reality. These Ayurvedic concepts allow physicians to examine the homeostasis of the whole system. People may be of a predominant dosha prakruti (constitution), but all doshas have the basic elements within them.

5 types of vata dosha 5 types of pitta dosha 5 types of kapha dosha
  1. Prana Vata – Governs inhalation, perception through the senses and governs the mind. Located in the brain, head, throat, heart and respiratory organs.
  2. Udana Vata – Governs speech, self expression, effort, enthusiasm, strength and vitality. Located in the naval, lungs and throat.
  3. Samana Vata – Governs peristaltic movement of the digestive system. Located in the stomach and small intestines.
  4. Apana Vata – Governs all downward impulses (urination, elimination, menstruation, sexual discharges etc.) Located between the naval and the anus.
  5. Vyana Vata – Governs circulation, heart rhythm, locomotion. Centred in the heart and permeates through the whole body.
  1. Pachaka Pitta – Governs digestion of food which is broken down into nutrients and waste. Located in the lower stomach and small intestine.
  2. Ranjaka Pitta – Governs formation of red blood cells. Gives colour to blood and stools. Located in the liver, gallbladder and spleen.
  3. Alochaka Pitta – Governs visual perception. Located in the eyes.
  4. Sadhaka Pitta – Governs emotions such as contentment, memory, intelligence and digestion of thoughts. Located in the heart.
  5. Bharajaka Pitta – Governs lustre and complexion, temperature and pigmentation of the skin. Located in the skin.
  1. Kledaka Kapha – Governs moistening and liquefying of the food in the initial stages of digestion. Located in the upper part of the stomach.
  2. Avalambhaka Kapha – Governs lubrication of the heart and lungs. Provides strength to the back, chest and heart. Located in the chest, heart and lungs.
  3. Tarpaka Kapha – Governs calmness, happiness and stability. Nourishment of sense and motor organs. Located in the head, sinuses and cerebrospinal fluid.
  4. Bodhaka Kapha – Governs perception of taste, lubricating and moistening of food. Located in the tongue, mouth and throat
  5. Shleshaka Kapha – Governs lubrication of all joints. Located in the joints.

Notes and references

  1. Monier-Williams, Sanskrit-English Dictionary, Oxford, 1899
  2. http://www.ayurvedacollege.com/articles/drhalpern/Vata_Doshas Vata Dosha
  3. Monier-Williams, Sanskrit-English Dictionary, Oxford, 1899

आयुर्वेद

Ayurveda (Sanskrit Āyurveda आयुर्वेद, “lifeknowledge“; English pronunciation /ˌ.ərˈvdə/[1]) or Ayurvedic medicine is a system of Hindu traditional medicine of Vedic tradition,[2] is native to the Indian subcontinent, and is a form of alternative medicine. The oldest known Ayurvedic texts are the Suśrutha Saṃhitā and the Charaka Saṃhitā. These Classical Sanskrit texts are among the foundational and formally compiled works of Ayurveda.

By the medieval period, Ayurvedic practitioners developed a number of medicinal preparations and surgical procedures for the treatment of various ailments.[3] Practices that are derived from Ayurvedic medicine are regarded as part of complementary and alternative medicine,[4] and along with Siddha Medicine and Traditional Chinese medicine, forms the basis for systems medicine.[5]

There is no scientific evidence for the effectiveness of Ayurvedic medicine for the treatment of any disease.[6] Concerns have been raised about Ayurvedic products; for example, peer-reviewed studies have shown that up to 20% of Ayurvedic U.S. and Indian-manufactured patent medicines sold through the internet contained toxic levels of heavy metals such as lead, mercury and arsenic.[7][8]

Much like the medicine of classical antiquity, Ayurveda has historically taken the approach of enumerating bodily substances in the framework of the five classical elements (Sanskrit [maha]panchabhuta, viz. earth, water, fire, air and ether. Moreover, Ayurveda names seven basic tissues (dhatu). They are plasma (rasa), blood (rakta), muscles (māmsa), fat (meda), bone (asthi), marrow (majja), and semen (shukra).[18]

Ayurveda states that a balance of the three elemental substances, the Doshas, equals health, while imbalance equals disease. There are three doshas: Vata, Pitta and Kapha. One Ayurvedic theory states that each human possesses a unique combination of these doshas which define this person’s temperament and characteristics. Each person has a natural state, or natural combination of these three elements, and should seek balance by modulating their behavior or environment. In this way they can increase or decrease the doshas they lack or have an abundance of them respectively. Another view present in the ancient literature states that dosha equality is identical to health, and that persons with imbalance of dosha are proportionately unhealthy, because they are not in their natural state of balance. Prakriti is one of the most important concepts in Ayurveda.

There are three principal early texts on Ayurveda, all dating to the early centuries of the Common Era. These are the Charaka Samhita, the Sushruta Samhita and the medical portions of the Bower Manuscript (also known as the Bheda Samhita). The relative chronology of these texts is not entirely clear. The Charaka Samhita is often cited as primary; although it survived only as a recension dating to the 4th or 5th century, it may be based on an original written between 100 BCE and 100 CE, in which case it would predate the other two texts. The Sushruta Samhita was written in the 3rd or 4th century. The Bower Manuscript is of particular interest because here the manuscript itself is ancient, dated to the early 6th century.[36] The earliest documented mention of the name Sushruta is found in the Bower Manuscript.[37] The medical portions of the Bower Manuscript constitutes a collection of recipes which are connected to numerous ancient authorities, and may be based on an older medical tradition practiced during the Maurya period, antedating both the Charaka and the Sushruta Samhitas.

The Bower Manuscript is also of special interest to historians due to the presence of Indian medicine and its concepts in Central Asian Buddhism. A. F. R. Hoernle in his 1897 edition identified the scribe of the medical portions of the manuscript as a native of India, using a northern variant of the Gupta script, who had migrated and become a Buddhist monk in a monastery in Kucha. The Chinese pilgrim Fa Hsien (c. 337–422 AD) wrote about the health care system of the Gupta empire (320–550) and described the institutional approach of Indian medicine, also visible in the works of Charaka, who mentions a clinic and how it should be equipped.[38]

Other early texts, sometimes mentioned alongside the Sushruta, Chakaka and Bheda texts, are the Kasyapa and the Harita samhitas, presumably dating to the later Gupta period (ca. 6th century). Ayurvedic authors of the 7th or 8th century include Vagbhata and Madhava.[39]

No significant scientific evidence has shown effectiveness of Ayurvedic medicine for the treatment of any disease, although massage and relaxation are often beneficial and there are indications of health effects from some herbal products used.[6] A systematic review of Ayurveda treatments for rheumatoid arthritis concluded that there was insufficient evidence, as most of the trials were not done properly, and the one high-quality trial showed no benefits.[73] A review of Ayurveda and cardiovascular disease concluded that the evidence for Ayurveda was not convincing, though some herbs seemed promising.[74]

Rasa shastra, the practice of adding metals, minerals or gems to herbs, may include toxic heavy metals such as lead, mercury and arsenic.[8] Adverse reactions to herbs due to their pharmacology are described in traditional Ayurvedic texts, but Ayurvedic practitioners are reluctant to admit that herbs could be toxic and that reliable information on herbal toxicity is not readily available; there is a communication gap between modern medicine practitioners and Ayurvedic practitioners.[76]

According to a 1990 study on Ayurvedic medicines in India, 41% of the products tested contained arsenic, and 64% contained lead and mercury.[48] A 2004 study found toxic levels of heavy metals in 20% of Ayurvedic preparations made in South Asia and sold in the Boston area; it concluded that Ayurvedic products posed serious health risks and should be tested for heavy-metal contamination.[77] A 2008 study of more than 230 products found that approximately 20% of remedies (and 40% of rasa shastra medicines) purchased over the Internet from U.S. and Indian suppliers contained lead, mercury or arsenic.[8][78][79] In 2012 the U.S. Centers for Disease Control and Prevention (CDC) linked Ayurvedic drugs to lead poisoning, based on some cases where toxic materials were found in the blood of pregnant women who had taken Ayurvedic drugs.[80]

Ayurvedic proponents believe that the toxicity of these materials is reduced through purification processes such as samskaras or shodhanas (for metals), similar to the Chinese pao zhi, although the Ayurvedic technique is more complex and may involve prayers as well as physical pharmacy techniques. However, these products have nonetheless caused severe lead poisoning and other toxic effects.[78][81]

Due to these concerns, the government of India ruled that Ayurvedic products must specify their metallic content directly on the labels of the product.[7] But, writing on the subject for Current Science, a publication of the Indian Academy of Sciences, M. S. Valiathan noted that “the absence of post-market surveillance and the paucity of test laboratory facilities [in India] make the quality control of Ayurvedic medicines exceedingly difficult at this time.”[7]

Most Ayurvedic products are labelled either for drug use (not FDA approved) or as dietary supplements. There is an import alert on some medicines issued by the FDA since 2007 which prevents these products entering the United States.[82]

 

The National Center for Complementary and Alternative Medicine (NCCAM)

The National Center for Complementary and Alternative Medicine (NCCAM), formerly the Office of Alternative Medicine (OAM), is a United States government agency that investigates complementary and alternative medicine (CAM) healing practices in the context of rigorous scientific methodology, in training complementary and alternative medicine researchers, and in disseminating authoritative information to the public and professionals.

The NCCAM is one of the 27 institutes and centers that make up the National Institutes of Health (NIH) within the Department of Health and Human Services of the federal government of the United States. The NIH is one of eight agencies under the Public Health Service (PHS) in the Department of Health and Human Services (DHHS).

The forms of medical systems covered include:[4]

External links

 

Phytotherapy

Phytotherapy is the study of the use of extracts of natural origin as medicines or health-promoting agents. Phytotherapy medicines differ from plant-derived medicines in standard pharmacology. Where standard pharmacology isolates an active compound from a given plant, phytotherapy aims to preserve the complexity of substances from a given plant with relatively less processing.

Phytotherapy is distinct from homeopathy and anthroposophic medicine, and avoids mixing plant and synthetic bioactive substances. Traditional phytotherapy is a synonym for herbalism and regarded as alternative medicine by much of Western medicine. Although the medicinal and biological effects of many plant constituents such as alkaloids (morphine, atropine etc.) have been proven through clinical studies, there is debate about the efficacy and the place of phytotherapy in medical therapies.

Many herbs have shown positive results in-vitro, animal model or small-scale clinical tests,[1] while studies on some herbal treatments have found negative results.[2]

In 2002, the U.S. National Center for Complementary and Alternative Medicine of the National Institutes of Health began funding clinical trials into the effectiveness of herbal medicine.[3] In a 2010 survey of 1000 plants, 356 had clinical trials published evaluating their “pharmacological activities and therapeutic applications” while 12% of the plants, although available in the Western market, had “no substantial studies” of their properties.[4]

Even widely used remedies may not have undergone substantial clinical testing. In a review on herbal medicine in Malaria treatment, the authors found that “…better evidence from randomised clinical trials is needed before herbal remedies can be recommended on a large scale. As such trials are expensive and time consuming, it is important to prioritise remedies for clinical investigation….”[5]

Modern phytotherapy, following the scientific method, can be considered the study on the effects and clinical use of herbal medicines.

Pudding

Pudding most often refers to a dessert, but it can also be a savory dish. In the United States, pudding characteristically denotes a sweet milk-based dessert similar in consistency to egg-based custards, though it may also refer to other types such as bread and rice pudding.
In the United Kingdom and some Commonwealth countries, pudding refers to rich, fairly homogeneous starch- or dairy-based desserts such as rice pudding and Christmas pudding, or, informally, any sweet dish after the main course. The word pudding in this context is also used as a synonym for the dessert course. The word is also used for savory dishes such as Yorkshire pudding, black pudding, suet pudding and steak and kidney pudding.
The word pudding is believed to come from the French boudin, originally from the Latin botellus, meaning “small sausage,” referring to encased meats used in Medieval European puddings.

Cobalamin (Vitamin B-12)

Vitamin B-12, or Cobalamin, is the largest and most complex vitamin currently known to man. A slight deficiency of vitamin B-12 can lead to anemia, fatigue, mania, and depression, while a long term deficiency can cause permanent damage to the brain and central nervous system. Vitamin B12 can only be manufactured by bacteria and can only be found naturally in animal products, however, synthetic forms are widely available and added to many foods like cereals. Vitamin B12 can be consumed in large doses because excess is excreted by the body or stored in the liver for use when supplies are scarce. Stores of B12 can last for up to a year. Below are the top 10 foods highest in vitamin B12 by common serving sizes, click here for high vitamin B12 foods by nutrient densityhere for an extended list of vitamin B12 rich foods, and here for other foods high in vitamin B. For even more see the articles for vegan and vegetarian sources of vitamin B12.


#1: Shellfish (Cooked Clams)

Vitamin B12 in 100g 3oz Serving (85g) Per 20 small clams (190g)
98.9μg (1648% DV) 84.1μg (1401% DV) 187.9μg (3132% DV)

Other Shellfish High in Vitamin B12 (%DV per 3oz serving cooked): Oysters (408%), and Mussels (340%). Click to see complete nutrition facts.



#2: Liver (Beef)

Vitamin B12 in 100g 3oz Serving (85g) Per Slice (81g)
83.1μg (1386% DV) 70.7μg (1178% DV) 67.3μg (1122% DV)

Other Liver Products High in Vitamin B12 (%DV per 3oz serving): Liverwurst Sausage (189%), Paté de Foie Gras (133%) and Chicken Liver Paté (114%). Click to see complete nutrition facts.



#3: Fish (Mackerel)

Vitamin B12 in 100g 3oz Serving (85g) Per Fillet (88g)
19.0μg (317% DV) 16.2μg (269% DV) 16.7μg (279% DV)

Other Fish High in Vitamin B12 (%DV per 3oz serving cooked): Smoked Salmon (257%), Herring (186%), Tuna (154%), Canned Sardines (126%) and Trout (106%). Click to see complete nutrition facts. For more see the article on Canned Fish High in Vitamin B12.



#4: Crustaceans (Crab)

Vitamin B12 in 100g 3oz Serving (85g) Per Leg (134g)
11.5μg (192% DV) 9.8μg (163% DV) 15.4μg (257% DV)

Other Crustaceans High in Vitamin B12 (%DV per 3oz serving cooked): Crayfish (44%), Shrimp (24%) and Lobster (20%). Click to see complete nutrition facts.



#5: Fortified Soy Products (Silken Tofu)

Vitamin B12 in 100g 3oz Serving (85g) Per 1/5 package (91g)
2.4μg (40% DV) 2.0μg (34% DV) 2.2μg (37% DV)

Light Plain Soymilk contains (50% DV) of Vitamin B12 per cupClick to see complete nutrition facts.



#6: Fortified Cereals (All Bran)

Vitamin B12 in 100g Per Cup (90g) Per Serving(1/3 Cup – 30g)
20.0μg (333% DV) 18.0μg (300% DV) 6.0μg (100% DV)

Click to see complete nutrition facts. For more see the article on Cereals High in B12.

#7: Red Meat (Beef)

Vitamin B12 in 100g 3oz Serving (85g) Per Medallion (34g)
6.0μg (100% DV) 5.1μg (85% DV) 2.0μg (34% DV)

Lamb is also High in Vitamin B12 with (45% DV) per 3oz serving cookedClick to see complete nutrition facts.



#8: Low Fat Dairy (Skim Milk)

Vitamin B12 in 100g Per Cup (245g) Per Quart (980g)
0.5μg (8% DV) 1.2μg (21% DV) 4.9μg (82% DV)

Other Dairy Foods High in Vitamin B12 (%DV per cup): Nonfat Yogurt (25%), Reduced Fat Milk (22%), Whole Milk (18%), and Full Fat Yogurt (15%). Click to see complete nutrition facts.



#9: Cheese (Swiss)

Vitamin B12 in 100g 1oz Serving (28g) Per Cup Shredded (108g)
3.3μg (56% DV) 0.9μg (16% DV) 3.6μg (60% DV)

Other Cheeses High in Vitamin B12 (%DV per 1 oz serving): Reduced Fat Mozzarella, Parmesan and Gietost (11%), Tilsit (10%) and Feta (8%). Click to see complete nutrition facts.



#10: Eggs (Chicken’s)

Vitamin B12 in 100g (Yolk) Per Yolk (17g) Per Whole Egg (50g)
2.0μg (33% DV) 0.3μg (6% DV) 0.36μg (6% DV)

Other Eggs High in Vitamin B12 (%DV per whole egg, raw): Goose (122%), Duck (63%), Turkey (22%), and Quail (2%). Click to see complete nutrition facts.
Read more at http://www.healthaliciousness.com/articles/foods-high-in-vitamin-B12.php#c1AIjCshFSfqQVHv.99

phytoestrogens

November 15, 2010

Kenneth Setchell

The importance of estrogens in homeostatic regulation of many cellular and biochemical events is well illustrated by the pathophysiologic changes that occur with estrogen deficiency. Many of the major diseases of Western populations are hormone dependent and epidemiologic data have shown a strong association between their incidence and diet. In particular, the importance of a plant-based diet is evident from the current dietary recommendations that emphasize an increase in the proportion and amount of fruit and vegetables that should be consumed. Although interpretation of the role of individual components of the diet is difficult from epidemiologic and dietary studies, it is recognized that there are many plant-derived bioactive nonnutrients that can confer significant health benefits. Among these phytochemicals is the broad class of nonsteroidal estrogens called phytoestrogens, and in the past decade there has been considerable interest in the role of isoflavones because of their relatively high concentrations in soy protein. The isoflavones in modest amounts of ingested soy protein are biotransformed by intestinal microflora, are absorbed, undergo enterohepatic recycling, and reach circulating concentrations
that exceed by several orders of magnitude the amounts of endogenous estrogens. These phytoestrogens and their
metabolites have many potent hormonal and nonhormonal activities that may explain some of the biological effects of diets rich in phytoestrogens

Low blood pressure

Blood pressure is a measurement of the pressure in your arteries during the active and resting phases of each heartbeat. Here’s what the numbers mean:

  • Systolic pressure. The first (top) number in a blood pressure reading, this is the amount of pressure your heart generates when pumping blood through your arteries to the rest of your body.
  • Diastolic pressure. The second (bottom) number in a blood pressure reading, this refers to the amount of pressure in your arteries when your heart is at rest between beats.

Current guidelines identify normal blood pressure as lower than 120/80 mm Hg.

Although you can get an accurate blood pressure reading at any given time, blood pressure isn’t always the same. It can vary considerably in a short amount of time — sometimes from one heartbeat to the next, depending on body position, breathing rhythm, stress level, physical condition, medications you take, what you eat and drink, and even time of day. Blood pressure is usually lowest at night and rises sharply on waking.

Blood pressure: How low can you go?

What’s considered low blood pressure for you may be normal for someone else. Most doctors consider chronically low blood pressure too low only if it causes noticeable symptoms.

Some experts define low blood pressure as readings lower than 90 mm Hg systolic or 60 mm Hg diastolic — you need to have only one number in the low range for your blood pressure to be considered lower than normal. In other words, if your systolic pressure is a perfect 115, but your diastolic pressure is 50, you’re considered to have lower than normal pressure.

A sudden fall in blood pressure also can be dangerous. A change of just 20 mm Hg — a drop from 110 systolic to 90 mm Hg systolic, for example — can cause dizziness and fainting when the brain fails to receive an adequate supply of blood.

And big plunges, especially those caused by uncontrolled bleeding, severe infections or allergic reactions, can be life-threatening.

Athletes and people who exercise regularly tend to have lower blood pressure and a slower heart rate than do people who aren’t as fit. So, in general, do nonsmokers and people who eat a healthy diet and maintain a normal weight.

But in some rare instances, low blood pressure can be a sign of serious, even life-threatening disorders.

Conditions that can cause low blood pressure

Some medical conditions can cause low blood pressure. These include:

  • Pregnancy. Because a woman’s circulatory system expands rapidly during pregnancy, blood pressure is likely to drop. This is normal, and blood pressure usually returns to your pre-pregnancy level after you’ve given birth.
  • Heart problems. Some heart conditions that can lead to low blood pressure include extremely low heart rate (bradycardia), heart valve problems, heart attack and heart failure.These conditions may cause low blood pressure because they prevent your body from being able to circulate enough blood.
  • Endocrine problems. Thyroid conditions — such as parathyroid disease — adrenal insufficiency (Addison’s disease), low blood sugar (hypoglycemia) and, in some cases, diabetes can trigger low blood pressure.
  • Dehydration. When you become dehydrated, your body loses more water than it takes in. Even mild dehydration can cause weakness, dizziness and fatigue. Fever, vomiting, severe diarrhea, overuse of diuretics and strenuous exercise can all lead to dehydration.Far more serious is hypovolemic shock, a life-threatening complication of dehydration. It occurs when low blood volume causes a sudden drop in blood pressure and a reduction in the amount of oxygen reaching your tissues. If untreated, severe hypovolemic shock can cause death within a few minutes or hours.
  • Blood loss. Losing a lot of blood from a major injury or internal bleeding reduces the amount of blood in your body, leading to a severe drop in blood pressure.
  • Severe infection (septicemia). Septicemia can happen when an infection in the body enters the bloodstream. This condition can lead to a life-threatening drop in blood pressure called septic shock.
  • Severe allergic reaction (anaphylaxis). Anaphylaxis is a severe and potentially life-threatening allergic reaction. Common triggers of anaphylaxis include foods, certain medications, insect venoms and latex. Anaphylaxis can cause breathing problems, hives, itching, a swollen throat and a drop in blood pressure.
  • Lack of nutrients in your diet. A lack of the vitamins B-12 and folate can cause a condition in which your body doesn’t produce enough red blood cells (anemia), causing low blood pressure.

Medications that can cause low blood pressure

Some medications you may take can also cause low blood pressure, including:

  • Diuretics (water pills), such as furosemide (Lasix) and hydrochlorothiazide (Microzide, Oretic)
  • Alpha blockers, such as prazosin (Minipress) and labetalol
  • Beta blockers, such as atenolol (Tenormin), propranolol (Inderal, Innopran XL, others) and timolol
  • Drugs for Parkinson’s disease, such as pramipexole (Mirapex) or those containing levodopa
  • Certain types of antidepressants (tricyclic antidepressants), including doxepin (Silenor), imipramine (Tofranil), protriptyline (Vivactil) and trimipramine (Surmontil)
  • Sildenafil (Viagra) or tadalafil (Cialis), particularly in combination with the heart medication nitroglycerin

Types of low blood pressure

Doctors often break down low blood pressure (hypotension) into different categories, depending on the causes and other factors. Some types of low blood pressure include:

  • Low blood pressure on standing up (orthostatic, or postural, hypotension). This is a sudden drop in blood pressure when you stand up from a sitting position or if you stand up after lying down.Ordinarily, gravity causes blood to pool in your legs whenever you stand. Your body compensates for this by increasing your heart rate and constricting blood vessels, thereby ensuring that enough blood returns to your brain.

    But in people with orthostatic hypotension, this compensating mechanism fails and blood pressure falls, leading to symptoms of dizziness, lightheadedness, blurred vision and even fainting.

    Orthostatic hypotension can occur for a variety of reasons, including dehydration, prolonged bed rest, pregnancy, diabetes, heart problems, burns, excessive heat, large varicose veins and certain neurological disorders.

    A number of medications also can cause orthostatic hypotension, particularly drugs used to treat high blood pressure — diuretics, beta blockers, calcium channel blockers and angiotensin-converting enzyme (ACE) inhibitors — as well as antidepressants and drugs used to treat Parkinson’s disease and erectile dysfunction.

    Orthostatic hypotension is especially common in older adults, with as many as 20 percent of those older than age 65 experiencing orthostatic hypotension.

    But orthostatic hypotension can also affect young, otherwise healthy people who stand up suddenly after sitting with their legs crossed for long periods or after working for a time in a squatting position.

  • Low blood pressure after eating (postprandial hypotension). Postprandial hypotension is a sudden drop in blood pressure after eating. It affects mostly older adults.Just as gravity pulls blood to your feet when you stand, a large amount of blood flows to your digestive tract after you eat.

    Ordinarily, your body counteracts this by increasing your heart rate and constricting certain blood vessels to help maintain normal blood pressure. But in some people these mechanisms fail, leading to dizziness, faintness and falls.

    Postprandial hypotension is more likely to affect people with high blood pressure or autonomic nervous system disorders such as Parkinson’s disease.

    Lowering the dose of blood pressure drugs and eating small, low-carbohydrate meals may help reduce symptoms.

  • Low blood pressure from faulty brain signals (neurally mediated hypotension). This disorder causes blood pressure to drop after standing for long periods, leading to signs and symptoms such as dizziness, nausea and fainting.Neurally mediated hypotension mostly affects young people, and it seems to occur because of a miscommunication between the heart and the brain.

    When you stand for extended periods, your blood pressure falls as blood pools in your legs. Normally, your body then makes adjustments to normalize your blood pressure.

    But in people with neurally mediated hypotension, nerves in the heart’s left ventricle actually signal the brain that blood pressure is too high, rather than too low.

    As a result, the brain lessens the heart rate, decreasing blood pressure even further. This causes more blood to pool in the legs and less blood to reach the brain, leading to lightheadedness and fainting.

  • Low blood pressure due to nervous system damage (multiple system atrophy with orthostatic hypotension).Also called Shy-Drager syndrome, this rare disorder causes progressive damage to the autonomic nervous system, which controls involuntary functions such as blood pressure, heart rate, breathing and digestion.Although this condition can be associated with muscle tremors, slowed movement, problems with coordination and speech, and incontinence, its main characteristic is severe orthostatic hypotension in combination with very high blood pressure when lying down.